Genetics : from genes to genomes / Leland H. Hartwell ... [et al.]

Includes index.

Includes bibliographical references and index.

Genetics: the study of biological information -- Mendel's breakthrough: patterns, particles, and principles of heredity -- Extensions to mendel: complexities in relating genotype to phenotype -- The chromosome theory of inheritance -- Linkage, recombination, and the the mapping of genes on chromosomes -- DNA: how the molecule of heredity carries, replicates, and recombines information -- Anatomy and function of a gene: dissection through mutation -- Gene expression: the flow of genetic information from DNA to RNA to protein -- Deconstructing the genome: DNA at high resolution -- Reconstructing the genome through genetic and molecular analysis -- The direct detection of genotype distinguishes individual genomes -- Systems biology and proteomics -- The eukaryotic chromosome: an organelle for packaging and managing DNA -- Chromosomal rearrangements and changes in chromosome number reshape eukaryotic genomes -- The prokaryotic chromosome: genetic analysis in bacteria -- The chromosomes of organelles outside the nucleus exhibit non-mendelian patterns of inheritance -- Gene regulation in prokaryotes -- Gene regulation in eukaryotes -- Cell-cycle regulation and the genetics of cancer -- Using genetics to study development -- The genetic analysis of populations and how they evolve -- Evolution at the molecular level.